BASS XXIX Tutorials and Keynote Address presentations: SessionSpeakerPresentation Keynote AddressLisa LaVange Leadership in Innovation and Collaboration M-1Steve Ruberg The Epistemological Superiority of Bayesian Inference Over Frequentist Inference M-2Brian Hobbs Leveraging Historical Controls Using Multi-source Adaptive Design M-4Kao-Tai Tsai, Network Analysis of RNA Sequence and Drug Safety Data T-1Brent McHenryCombination Complexities, Contribution of Components Considerations in Cancer: Gleanings from Interactions with Health Authorities at Various Stages of Development T-2Jing Zhao Contribution of Components in Different Perspectives: From Individual Investigational Drugs and From Different Treatment Periods T-3Jinjie Chen DOME: A Bayesian Optimal Design for Randomized Dose Expansion Cohorts in Oncology Trials T-4Parvin Fardipour Sample Size Re-estimation in the Context of Dual Endpoints Using a Promising Zone Approach – Illustrated with Two Pharmaceutical Case Studies T-5Shankar Srinavasan Inverse Propensity Score-Based Weighting Methods to Remove Bias in Observational Studies T-6Ben Duncan Robust Safety Monitoring and Signal Detection Using Alternatives to the Standard Poisson Distribution W-1Rebecca Hagar Recommendations and Considerations for Umbrella and Platform Trials W-2Cesar Torres A CDER Reviewer's Experience With COVID-19 Programs W-3Xin Wang Overall Type I Error Control for Seamless Phase II/III Adaptive Design using Biomarkers ← 2021